Combined proteomic and transcriptomic analysis of the response of Bacillus anthracis to oxidative stress.

@article{Pohl2011CombinedPA,
  title={Combined proteomic and transcriptomic analysis of the response of Bacillus anthracis to oxidative stress.},
  author={Susanne Pohl and Wang Yung Tu and Phillip D Aldridge and Colin Gillespie and H. Hahne and Ulrike M{\"a}der and Timothy D. Read and Colin R. Harwood},
  journal={Proteomics},
  year={2011},
  volume={11 15},
  pages={3036-55}
}
The endospore-forming Gram-positive pathogen Bacillus anthracis is responsible for the usually fatal disease, inhalational anthrax. The success of this pathogen is dependent on its ability to subvert elements of the innate immune system of its animal hosts. B. anthracis spores, which are the main infective agent, are engulfed and germinate in patrolling alveolar macrophages. In order for the infection to progress, the resulting vegetative cells must resist the antimicrobial oxidative burst… CONTINUE READING
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