Combined prophylaxis decreases incidence of CMV-associated pneumonia after lung transplantation.

@article{Solidoro2009CombinedPD,
  title={Combined prophylaxis decreases incidence of CMV-associated pneumonia after lung transplantation.},
  author={Paolo Solidoro and Luisa Delsedime and Massimiliano Bergallo and Daniela Libertucci and Enrico Ruffini and Cristina Tom{\'a}s da Costa and Mauro Rinaldi and Antonio Amoroso and Sergio Baldi},
  journal={Transplantation proceedings},
  year={2009},
  volume={41 4},
  pages={1347-8}
}
Among solid-organ recipients, those with lung transplants are at highest risk of cytomegalovirus (CMV) infection or to die of CMV-associated disease. We evaluated the effect of combined CMV antiviral prophylaxis and CMV-immunoglobulin prophylaxis on CMV-associated pneumonia diagnosed in 303 follow-up transbronchial biopsy (TBB) specimens from lung transplant recipients. At our center, 24 recipients (control group; 1999-2002) received acyclovir for 24 months and 33 recipients (study group; 2003… CONTINUE READING

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