Combined photothermal and antibiotic therapy for bacterial infection via acidity-sensitive nanocarriers with enhanced antimicrobial performance

@inproceedings{He2018CombinedPA,
  title={Combined photothermal and antibiotic therapy for bacterial infection via acidity-sensitive nanocarriers with enhanced antimicrobial performance},
  author={Danfeng He and Tao Yang and Wei Qian and Chao Qi and Li Mao and Xunzhou Yu and Huifeng Zhu and Gaoxing Luo and Jun Hua Deng},
  year={2018}
}
Abstract Integration of two distinctive bactericides into one platform is a promising strategy to enhance the efficiency of antimicrobial agents. We reported an efficient chemo-photothermal therapeutic platform based on polydopamine (PDA)-coated gold nanorods (PDA@GNRs). Then the PDA@GNRs were further grafted with glycol chitosan (GCS-PDA@GNRs), which became positively charged in the low pH environment of bacterial infection sites, allowing them to accumulate/retain at local infection site as… CONTINUE READING

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