Combined pancreatic islet-lung transplantation: a novel approach to the treatment of end-stage cystic fibrosis.

@article{Kessler2010CombinedPI,
  title={Combined pancreatic islet-lung transplantation: a novel approach to the treatment of end-stage cystic fibrosis.},
  author={Laurence Kessler and S Bakopoulou and Romain Kessler and Gilbert Massard and Nicola Santelmo and Michel Greget and François Moreau and Olivier Helms and Domenico Bosco and Paola Marina Alessandra Gasche-Soccal and Philippe M Morel and Philippe Wolf and Thierry Berney},
  journal={American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons},
  year={2010},
  volume={10 7},
  pages={
          1707-12
        }
}
Patients with end-stage cystic fibrosis (CF) and severe CF-related diabetes (CFRD) may benefit from combined lung-pancreatic islet transplantation. In the present study, we report the long-term follow-up of four end-stage CF patients treated with combined bilateral lung and pancreatic islet transplantation from the same donor. All patients were C-peptide negative (<0.5 microg/L) and inadequately controlled despite intensive insulin treatment. One patient was transplanted with 4 019 +/- 490… CONTINUE READING

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