Combined irinotecan and oxaliplatin in patients with advanced pre-treated pancreatic cancer.

@article{Cantore2004CombinedIA,
  title={Combined irinotecan and oxaliplatin in patients with advanced pre-treated pancreatic cancer.},
  author={Maurizio Cantore and Carla Rabbi and Giammaria Fiorentini and Cristina Oliani and Donatella Zamagni and Calogero Iacono and Andrea Mambrini and Alfonso Del Freo and Ahmed Manni},
  journal={Oncology},
  year={2004},
  volume={67 2},
  pages={93-7}
}
OBJECTIVES This study evaluated the clinical activity and toxicity of combination chemotherapy with irinotecan and oxaliplatin in patients with advanced pancreatic cancer that had progressed despite > or =1 course of a gemcitabine-containing regimen. METHODS Thirty patients with metastatic pancreatic cancer and Karnofsky performance status > or =70 received oxaliplatin 60 mg/m2 on days 1 + 15 and irinotecan 60 mg/m2 on days 1 + 8 + 15 every 4 weeks. Patients were assessed on the basis of… CONTINUE READING

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