Combined intravenous and oral mesna in outpatients treated with ifosfamide

Abstract

Purpose: To prevent hemorrhagic cystitis, mesna is typically injected intravenously (IV) at the time of an ifosfamide dose and 4 and 8 h later. To simplify outpatient ifosfamide therapy, we gave the second and third mesna doses orally. Methods: The mesna doses (400 or 600 mg/m2) were 40% (w/w) of each ifosfamide dose (1.0 or 1.5 g/m2), which was given daily… (More)
DOI: 10.1007/s002800050673

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Cite this paper

@article{Goren1997CombinedIA, title={Combined intravenous and oral mesna in outpatients treated with ifosfamide}, author={Marshall P. Goren and Linda M. McKenna and Thomas L. Goodman}, journal={Cancer Chemotherapy and Pharmacology}, year={1997}, volume={40}, pages={371-375} }