• Medicine
• Published in
  American journal of…
  2000
• DOI:10.1152/ajpendo.2000.278.3.E544

Combined intraportal infusion of acetylcholine and adrenergic blockers augments net hepatic glucose uptake.

@article{Shiota2000CombinedII,
  title={Combined intraportal infusion of acetylcholine and adrenergic blockers augments net hepatic glucose uptake.},
  author={Masakazu Shiota and P A Jackson and Pietro Renato Galassetti and M Scott and Doss W. Neal and Alan D. Cherrington},
  journal={American journal of physiology. Endocrinology and metabolism},
  year={2000},
  volume={278 3},
  pages={
          E544-52
        }
}

• Masakazu Shiota, P A Jackson, +3 authors Alan D. Cherrington

Portal glucose delivery in the conscious dog augments net hepatic glucose uptake (NHGU). To investigate the possible role of altered autonomic nervous activity in the effect of portal glucose delivery, the effects of adrenergic blockade and acetylcholine (ACh) on hepatic glucose metabolism were examined in 42-h-fasted conscious dogs. Each study consisted of an equilibration (-120 to -20 min), a control (-20 to 0 min), and a hyperglycemic-hyperinsulinemic period (0 to 300 min). During the last… CONTINUE READING

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