Combined intervention with pioglitazone and n-3 fatty acids in metformin-treated type 2 diabetic patients: improvement of lipid metabolism

@inproceedings{Veleba2015CombinedIW,
  title={Combined intervention with pioglitazone and n-3 fatty acids in metformin-treated type 2 diabetic patients: improvement of lipid metabolism},
  author={Jiri Veleba and Petra Janovsk{\'a} and Ondrej Kuda and Olga Horakova and Hana Mal{\'i}nsk{\'a} and Ludmila Kazdov{\'a} and Olena Oliyarnyk and Vojtěch {\vS}kop and Jaroslava Trnovsk{\'a} and Milan H{\'a}jek and Antonin Skoch and Pavel Flachs and Kristina Bardov{\'a} and Martin Rossmeisl and Josune Olza and Gabriela Salim Ferreira de Castro and Philip C Calder and Al{\vz}běta Gardlo and Eva Fiserov{\'a} and J\orgen Grue Jensen and Morten Bryhn and J{\'a}n Kopeck{\'y} and Terezie Pelik{\'a}nov{\'a}},
  booktitle={Nutrition & metabolism},
  year={2015}
}
BACKGROUND The marine n-3 fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) exert numerous beneficial effects on health, but their potency to improve treatment of type 2 diabetic (T2D) patients remains poorly characterized. We aimed to evaluate the effect of a combination intervention using EPA + DHA and the insulin-sensitizing drug pioglitazone in overweight/obese T2D patients already treated with metformin. METHODS In a parallel-group, four-arm, randomized trial, 69… CONTINUE READING
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