Combined insulin treatment and intense exercise training improved basal cardiac function and Ca(2+)-cycling proteins expression in type 1 diabetic rats.

@article{Lahaye2012CombinedIT,
  title={Combined insulin treatment and intense exercise training improved basal cardiac function and Ca(2+)-cycling proteins expression in type 1 diabetic rats.},
  author={Sol{\`e}ne Le Douairon Lahaye and Arlette Gratas-Delamarche and Ludivine Malard{\'e} and Sami Zguira and Sophie Vincent and Sophie Lemoine Morel and François Carr{\'e} and Françoise Rannou Bekono},
  journal={Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme},
  year={2012},
  volume={37 1},
  pages={53-62}
}
This study investigated the effects of 8 weeks of intense exercise training combined with insulin treatment on the Ca(2+)-cycling protein complex expression and their functional consequences on cardiac function in type 1 diabetic rat hearts. Diabetic Wistar rats were randomly assigned into the following groups: received no treatment, insulin-treated diabetic, trained diabetic, and trained insulin-treated diabetic. A control group was also included. Insulin treatment and (or) treadmill intense… CONTINUE READING

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