• Medicine
  • Published 2007

Combined inhibitory effects of celecoxib and 5-fluorouracil on growth of human hepatic carcinoma cell line HepG2

@inproceedings{Zhiyuan2007CombinedIE,
  title={Combined inhibitory effects of celecoxib and 5-fluorouracil on growth of human hepatic carcinoma cell line HepG2},
  author={Xu Zhi-yuan},
  year={2007}
}
OBJECTIVE:To observe the combination effects of 5-fluorouracil (5-FU) and celecoxib in human hepatocellular carcinoma cell line HepG2 in vitro. METHODS: The combination effects and the interaction between celecoxib and 5-FU on HepG2 cells were evaluated according to the median-efffect principle. RESULTS: When celecoxib or 5-FU was used alone, the resulting curves showed that both agents had the concentration-dependent inhibitory effect . The celecoxib concentration inhibiting 50 % of the growth… CONTINUE READING

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