Combined in utero and juvenile exposure of mice to arsenate and atrazine in drinking water modulates gene expression and clonogenicity of myeloid progenitors.

@article{CiminoReale2008CombinedIU,
  title={Combined in utero and juvenile exposure of mice to arsenate and atrazine in drinking water modulates gene expression and clonogenicity of myeloid progenitors.},
  author={Graziella Cimino-Reale and Daniele Ferrario and Barbara Casati and Roberta Brustio and Cristina Diodovich and Angelo Collotta and Marie Vahter and Laura Gribaldo},
  journal={Toxicology letters},
  year={2008},
  volume={180 1},
  pages={59-66}
}
The effects of arsenate (As) and atrazine (Atr) on myeloid progenitors (colony-forming unit-granulocyte/macrophage, CFU-GM) cells derived from bone marrow were studied in male and female mice after combined in utero and juvenile exposure. Female adult mice were treated with arsenate in drinking water during gestation. Then, separate groups of males and females' offspring were exposed for 4 months to atrazine, to additional arsenate or to co-exposure of atrazine and arsenate together in drinking… CONTINUE READING

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