Combined hemorrhagic shock and head injury: effects of hypertonic saline (7.5%) resuscitation.

@article{Battistella1991CombinedHS,
  title={Combined hemorrhagic shock and head injury: effects of hypertonic saline (7.5%) resuscitation.},
  author={Felix D. Battistella and David H. Wisner},
  journal={The Journal of trauma},
  year={1991},
  volume={31 2},
  pages={182-8}
}
Hypertonic saline resuscitation was compared to isotonic fluid resuscitation in a large animal model combining hemorrhagic shock with head injury. Sheep were subjected to a freeze injury of one cerebral hemisphere as well as 2 hours of hypotension at a mean arterial pressure (MAP) of 40 mm Hg. Resuscitation was then carried out (MAP = 80 mm Hg) for 1 hour with either lactated Ringer's (LR, n = 6) or 7.5% hypertonic saline (HS, n = 6). Hemodynamic parameters and intracranial pressure (ICP) were… CONTINUE READING
24 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 24 extracted citations

Similar Papers

Loading similar papers…