Combined examination of p27(Kip1), p21(Waf1/Cip1) and p53 expression allows precise estimation of prognosis in patients with gastric carcinoma.

@article{Liu2001CombinedEO,
  title={Combined examination of p27(Kip1), p21(Waf1/Cip1) and p53 expression allows precise estimation of prognosis in patients with gastric carcinoma.},
  author={Xiuping Liu and Shigeto Kawauchi and Atsunori Oga and Yutaka Suehiro and Kureo Tsushimi and Mutsuo Tsushimi and Kohsuke Sasaki},
  journal={Histopathology},
  year={2001},
  volume={39 6},
  pages={603-10}
}
AIMS In order to estimate the prognostic values of p27(Kip1), p21(Waf1/Cip1), and p53, alone and in combination, we investigated immunohistochemically the expression of p27(Kip1), p21(Waf1/Cip1), and p53 proteins in gastric carcinomas. METHODS AND RESULTS The expression of p27(Kip1), p21(Waf1/Cip1), and p53 was immunohistochemically examined in 140 gastric carcinomas. Positive expression of p27(Kip1) and p21(Waf1/Cip1) correlated significantly with a favourable prognosis (P < 0.05), whereas… CONTINUE READING

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