Combined effects of rat Schwann cells and 17β-estradiol in a spinal cord injury model

@article{Namjoo2018CombinedEO,
  title={Combined effects of rat Schwann cells and 17β-estradiol in a spinal cord injury model},
  author={Zeinab Namjoo and Fateme Moradi and Roya Aryanpour and Abbas Piryaei and Mohammad Taghi Joghataei and Yusef Abbasi and Amir Abbas Hosseini and Sajad Hassanzadeh and Fatemeh Ranjbar Taklimie and Cordian Beyer and Adib Zendedel},
  journal={Metabolic Brain Disease},
  year={2018},
  volume={33},
  pages={1229-1242}
}
Spinal cord injury (SCI) is a devastating traumatic event which burdens the affected individuals and the health system. Schwann cell (SC) transplantation is a promising repair strategy after SCI. However, a large number of SCs do not survive following transplantation. Previous studies demonstrated that 17β-estradiol (E2) protects different cell types and reduces tissue damage in SCI experimental animal model. In the current study, we evaluated the protective potential of E2 on SCs in vitro and… CONTINUE READING
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