Combined effects of curcumin and vitamin C to protect endothelial dysfunction in the iris tissue of STZ-induced diabetic rats.

@article{Patumraj2006CombinedEO,
  title={Combined effects of curcumin and vitamin C to protect endothelial dysfunction in the iris tissue of STZ-induced diabetic rats.},
  author={Suthiluk Patumraj and Natchaya Wongeakin and Patarin Sridulyakul and Amporn Jariyapongskul and Narisa Futrakul and Srichitra C Bunnag},
  journal={Clinical hemorheology and microcirculation},
  year={2006},
  volume={35 4},
  pages={
          481-9
        }
}
This study was aimed to evaluate the combined effect of curcumin with vitamin C supplementation on hyperglycemic and dyslipidemia conditions and endothelial cell dysfunction induced in diabetic rats. Wistar Furth rats were used and divided into four groups: control (single injection of 0.9% sterile saline), STZ (streptozotocin, Sigma, 55 mg/kg.BW, i.v.), STZ-vitC (1 g/l ascorbic acid mixed in drinking water), STZ-cur (daily oral treatment of 300 mg/kg.BW curcumin; Cayman Chemical Co., USA), and… CONTINUE READING

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