Combined effects of connective tissue growth factor-modified bone marrow-derived mesenchymal stem cells and NaOH-treated PLGA scaffolds on the repair of articular cartilage defect in rabbits.

@article{Zhu2014CombinedEO,
  title={Combined effects of connective tissue growth factor-modified bone marrow-derived mesenchymal stem cells and NaOH-treated PLGA scaffolds on the repair of articular cartilage defect in rabbits.},
  author={Songsong Zhu and Bin Zhang and Cheng Ning Man and Yongqing Ma and Xianwen Liu and Jing Hu},
  journal={Cell transplantation},
  year={2014},
  volume={23 6},
  pages={
          715-27
        }
}
In cartilage tissue engineering using stem cells, it is important to stimulate proliferation and control the differentiation of stem cells to specific lineages. Here we reported a combined technique for articular cartilage repair, consisting of bone marrow mesenchymal stem cells (BMMSCs) transfected with connective tissue growth factor (CTGF) gene and NaOH-treated poly(lactic-co-glycolic) acid (PLGA) scaffolds. In the present study, BMMSCs or CTGF-modified BMMSCs seeded on PLGA or NaOH-treated… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-9 OF 9 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 35 REFERENCES

Long-term survival and bipo- tent terminal differentiation of human mesenchymal stem cells (hMSC) in combination with a commercially avail- able three-dimensional collagen

  • R. Knüchel, A. Perez-Bouza
  • scaffold. Cell Transplant
  • 2008
1 Excerpt

Similar Papers

Loading similar papers…