Combined effects of ACE and MMP-3 polymorphisms on migraine development.

@article{Kara2007CombinedEO,
  title={Combined effects of ACE and MMP-3 polymorphisms on migraine development.},
  author={Ihsan Kara and Elif Ozkok and Muge Aydin and Nurcan Orhan and Yilmaz Çetinkaya and Mehmet Gencer and Gamze Kiliç and Hulya Tireli},
  journal={Cephalalgia : an international journal of headache},
  year={2007},
  volume={27 3},
  pages={235-43}
}
Migraine is a primary headache disorder which involves both genetic and environmental components. Since angiotensin-converting enzyme (ACE) and matrix metalloproteinase (MMP) share the same homology, we investigated whether the MMP-3 and ACE I/D gene variants are involved in migraine risk and whether the ACE variant might act in combination with the MMP-3… CONTINUE READING