Combined effect of the essential oil from Chenopodium ambrosioides and antileishmanial drugs on promastigotes of Leishmania amazonensis.

@article{Monzote2007CombinedEO,
  title={Combined effect of the essential oil from Chenopodium ambrosioides and antileishmanial drugs on promastigotes of Leishmania amazonensis.},
  author={Lianet Monzote and Ana M Montalvo and Ram{\'o}n Scull and Migdalia Miranda and Juan Abreu},
  journal={Revista do Instituto de Medicina Tropical de Sao Paulo},
  year={2007},
  volume={49 4},
  pages={257-60}
}
To date, there are no vaccines against Leishmania, and chemotherapy remains the mainstay for the control of leishmaniasis. The drugs of choice used for leishmaniasis therapy are significantly toxic, expensive and with a growing frequency of refractory infections. Because of these limitations, a combination therapy is the better hope. This work demonstrates that the essential oil from Chenopodium ambrosioides shows a synergic activity after incubation in conjunction with pentamidine against… CONTINUE READING