Combined effect of salinomycin and feeding on whole body glucose kinetics in sheep fed a high-concentrate diet.

@article{Fujita2006CombinedEO,
  title={Combined effect of salinomycin and feeding on whole body glucose kinetics in sheep fed a high-concentrate diet.},
  author={Tadahisa Fujita and Hiroya Majima and Takahiro Itoh and Hiroaki Sano},
  journal={Reproduction, nutrition, development},
  year={2006},
  volume={46 5},
  pages={
          503-14
        }
}
The aim of this study was to investigate the effects of salinomycin (SL) and feeding on whole body glucose kinetics in sheep fed a high-concentrate diet (25% orchardgrass hay and 75% commercial concentrate). Four adult sheep were fed the diet with or without 20 mg x kg(-1) diet of SL once daily for each 3 wk. The rates of glucose entry and utilization were determined before and during 3 h after feeding using a [ (13)C(6)] glucose dilution approach. Ruminal characteristics and concentrations of… 
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The high concentrates diet may increase hepatic gluconeogenesis in nonlactating goats, and there were no differences in net flow of glucose, BOHB and NEFA across splanchnic tissues, but a decreased net portal absorption in NEFA was observed.
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