Combined delivery approach of bone marrow mononuclear stem cells early and late after myocardial infarction: the MYSTAR prospective, randomized study

  title={Combined delivery approach of bone marrow mononuclear stem cells early and late after myocardial infarction: the MYSTAR prospective, randomized study},
  author={M. Gy{\"o}ngy{\"o}si and I. Lang and M. Dettke and G. Beran and S. Graf and H. Sochor and N. Nyolczas and S. Charwat and R. Hemetsberger and G. Christ and I. Edes and L. Balogh and K. Krause and K. Jaquet and K. Kuck and I. Benedek and T. Hintea and R. Kiss and I. Pr{\'e}da and V. Kotevski and H. Pejkov and Sholeh Zamini and A. Khorsand and G. Sodeck and A. Kaider and G. Maurer and D. Glogar},
  journal={Nature Clinical Practice Cardiovascular Medicine},
  • M. Gyöngyösi, I. Lang, +24 authors D. Glogar
  • Published 2009
  • Medicine
  • Nature Clinical Practice Cardiovascular Medicine
  • Background Combined intracoronary and intramyocardial administration might improve outcomes for bone-marrow-derived stem cell therapy for acute myocardial infarction (AMI). We compared the safety and feasibility of early and late delivery of stem cells with combined therapy approaches.Methods Patients with left ventricular ejection fraction less than 45% after AMI were randomly assigned stem cell delivery via intramyocardial injection and intracoronary infusion 3–6 weeks or 3–4 months after AMI… CONTINUE READING
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