Combined delivery approach of bone marrow mononuclear stem cells early and late after myocardial infarction: the MYSTAR prospective, randomized study

@article{Gyngysi2009CombinedDA,
  title={Combined delivery approach of bone marrow mononuclear stem cells early and late after myocardial infarction: the MYSTAR prospective, randomized study},
  author={Mariann Gy{\"o}ngy{\"o}si and Ir{\'e}ne Lang and Markus Dettke and Gilbert Beran and Senta Graf and Heinz Sochor and No{\'e}mi Nyolczas and Silvia Charwat and Rayyan Hemetsberger and Guenter Christ and Istvan Edes and L{\'a}szl{\'o} Balogh and Korff Thomas Krause and Kai Jaquet and Karl-heinz Kuck and Imre Benedek and Theodora Hintea and R{\'o}bert Kiss and Istv{\'a}n Pr{\'e}da and Vladimir Kotevski and Hristo Pejkov and S. Zamini and Aliasghar Khorsand and Gottfried H. Sodeck and Alexandra Kaider and Gerald Maurer and Dietmar Glogar},
  journal={Nature Clinical Practice Cardiovascular Medicine},
  year={2009},
  volume={6},
  pages={70-81}
}
Background Combined intracoronary and intramyocardial administration might improve outcomes for bone-marrow-derived stem cell therapy for acute myocardial infarction (AMI). We compared the safety and feasibility of early and late delivery of stem cells with combined therapy approaches.Methods Patients with left ventricular ejection fraction less than 45% after AMI were randomly assigned stem cell delivery via intramyocardial injection and intracoronary infusion 3–6 weeks or 3–4 months after AMI… CONTINUE READING

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