Combined deficiency of iron and (n-3) fatty acids in male rats disrupts brain monoamine metabolism and produces greater memory deficits than iron deficiency or (n-3) fatty acid deficiency alone.

@article{Baumgartner2012CombinedDO,
  title={Combined deficiency of iron and (n-3) fatty acids in male rats disrupts brain monoamine metabolism and produces greater memory deficits than iron deficiency or (n-3) fatty acid deficiency alone.},
  author={Jeannine Baumgartner and Cornelius M Smuts and Linda Malan and Myrtha M Arnold and Benjamin K. Yee and Laura E Bianco and Mark V. Boekschoten and Michael M{\"u}ller and Wolfgang Langhans and Richard F Hurrell and Michael Zimmermann},
  journal={The Journal of nutrition},
  year={2012},
  volume={142 8},
  pages={1463-71}
}
Deficiencies of iron (Fe) (ID) and (n-3) fatty acids (FA) [(n-3)FAD] may impair brain development and function through shared mechanisms. However, little is known about the potential interactions between these 2 common deficiencies. We studied the effects of ID and (n-3)FAD, alone and in combination, on brain monoamine pathways (by measuring monoamines and related gene expression) and spatial working and reference memory (by Morris water maze testing). Using a 2 × 2 design, male rats were fed… CONTINUE READING
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Iron deficiency and neuropharmacology. In: Iron deficiency and overload: from basic biology to clinical medicine

  • LE Bianco, EL Unger, J. Beard
  • 2010
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