Combined chemotherapy and radiation therapy for CNS germ cell tumors – the Japanese experience

@article{Matsutani2001CombinedCA,
  title={Combined chemotherapy and radiation therapy for CNS germ cell tumors – the Japanese experience},
  author={Masao Matsutani and The Japanese Pediatric Brain Tumor Study Group},
  journal={Journal of Neuro-Oncology},
  year={2001},
  volume={54},
  pages={311-316}
}
Among intracranial germ cell tumors, nongerminomatous tumors have proved refractory to conventional treatment with surgery and irradiation. The median survival is less than 2 years. Since 1983, chemotherapy has been delivered in Japan as an adjuvant therapy in patients with intracranial nongerminomatous germ cell tumors. Based on our clinical experience, we undertook a multi-institutional phase II study to establish post-surgical combined chemotherapy and radiation therapy for primary germ cell… CONTINUE READING

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