Combined antifungal therapy in a murine infection by Candida glabrata.

Abstract

OBJECTIVES To develop proper treatments for patients who do not respond to current antifungal treatments, we tested new combinations of antifungal drugs for treating disseminated infections by Candida glabrata in a murine model. METHODS Mice were rendered neutropenic by intraperitoneal cyclophosphamide and intravenous 5-fluorouracil administration. The… (More)

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