Combined analysis of three crossover clinical pharmacology studies of effects of rabeprazole and esomeprazole on 24-h intragastric pH in healthy volunteers.

Abstract

AIM To compare antisecretory effects of rabeprazole and esomeprazole after single and repeat dosing in Helicobacter pylori-negative healthy volunteers. METHODS Results were pooled from three smaller, open, crossover, randomized studies to obtain data from 80 subjects. The studies compared: (a) 5 days' dosing of 20 mg rabeprazole and esomeprazole (n = 24… (More)

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@article{Norris2007CombinedAO, title={Combined analysis of three crossover clinical pharmacology studies of effects of rabeprazole and esomeprazole on 24-h intragastric pH in healthy volunteers.}, author={Virginia H. Norris and Kathy J. Baisley and Kate M Dunn and Stephanie D. Warrington and Anna Morocutti}, journal={Alimentary pharmacology & therapeutics}, year={2007}, volume={25 4}, pages={501-10} }