Combined analysis of cytokine genotype polymorphism and the level of expression with allograft function in African-American renal transplant patients.

@article{McDaniel2003CombinedAO,
  title={Combined analysis of cytokine genotype polymorphism and the level of expression with allograft function in African-American renal transplant patients.},
  author={D. Olga McDaniel and William Henry Barber and C Nguyan and Stephanie Rhodes and Warren L. May and Larry S McDaniel and Parminder J. S. Vig and L L Jemeson and Donald E Butkus},
  journal={Transplant immunology},
  year={2003},
  volume={11 1},
  pages={107-19}
}
Cytokine gene polymorphism and expression levels were evaluated in a group of African-American patients who had undergone renal transplantation. It was hypothesized that possession of specific cytokine alleles might be influential in predisposing the recipient to allograft rejection. Thus, we sought to establish a relationship between cytokine gene polymorphism, the levels of cytokine expression, and the outcome of allograft function. Cytokine genotypes and mRNA transcript levels of IL-2, TNF… CONTINUE READING