Combined analysis of chromosomal aberrations and glutathione S-transferase M1 and T1 polymorphisms in pathologists occupationally exposed to formaldehyde

@article{Santovito2011CombinedAO,
  title={Combined analysis of chromosomal aberrations and glutathione S-transferase M1 and T1 polymorphisms in pathologists occupationally exposed to formaldehyde},
  author={Alfredo Santovito and Tiziana Schilir{\`o} and Sergio Castellano and Piero Cervella and Maria Paola Bigatti and Giorgio Gilli and Roberto Bono and Massimiliano Delpero},
  journal={Archives of Toxicology},
  year={2011},
  volume={85},
  pages={1295-1302}
}
The formaldehyde (FA) genotoxic potential in occupationally exposed individuals is conflicting. A relevant indoor-air FA pollution was found in hospitals and scientific institutions where FA is used as a bactericide and tissue preservative. In the present study, we evaluated the frequency of chromosomal aberrations (CAs) in peripheral blood lymphocytes from workers in pathology wards who have been exposed to FA, compared with a group of unexposed subjects. The subjects were also analyzed for… CONTINUE READING
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