Combined analysis of CHRNA5, CHRNA3 and CYP2A6 in relation to adolescent smoking behaviour.

@article{Rodriguez2011CombinedAO,
  title={Combined analysis of CHRNA5, CHRNA3 and CYP2A6 in relation to adolescent smoking behaviour.},
  author={Santiago Rodriguez and Derek G. Cook and Tom R. Gaunt and Claire M Nightingale and Peter Whincup and I. N. Day},
  journal={Journal of psychopharmacology},
  year={2011},
  volume={25 7},
  pages={915-23}
}
CYP2A6 influences smoking uptake in adolescence. Genetic variation in the CHRNA5-CHRNA3 region influences smoking behaviour in adults. However, their combined effects on smoking in adolescence have not been tested to date. We present data on 1450 adolescents from the Ten Towns Heart Health Study (TTHHS) extensively phenotyped for smoking-related traits during adolescence. Single nucleotide polymorphisms from CHRNA5 and CHRNA3 (previously associated with smoking), were typed in our study… CONTINUE READING

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