Combined Use of Mycobacterium tuberculosis–Specific CD4 and CD8 T-Cell Responses Is a Powerful Diagnostic Tool of Active Tuberculosis

@inproceedings{Rozot2015CombinedUO,
  title={Combined Use of Mycobacterium tuberculosis–Specific CD4 and CD8 T-Cell Responses Is a Powerful Diagnostic Tool of Active Tuberculosis},
  author={Virginie Rozot and Amelio Patrizia and Selena Vigan{\`o} and Jesica Mazza-Stalder and Elita Idrizi and Cheryl L. Day and Matthieu Perreau and Catherine Lazor-Blanchet and Khalid Ohmiti and Delia Goletti and Pierre-Alexandre Bart and Willem A Hanekom and Thomas J Scriba and Laurent P. Nicod and Giuseppe Pantaleo and Alexandre Harari},
  booktitle={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  year={2015}
}
Immune-based assays are promising tools to help to formulate diagnosis of active tuberculosis. A multiparameter flow cytometry assay assessing T-cell responses specific to Mycobacterium tuberculosis and the combination of both CD4 and CD8 T-cell responses accurately discriminated between active tuberculosis and latent infection. 

Figures and Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 26 CITATIONS

Frequency of Mycobacterium tuberculosis-specific CD8+ T-cells in the course of anti-tuberculosis treatment.

  • International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
  • 2015
VIEW 8 EXCERPTS
CITES BACKGROUND & RESULTS
HIGHLY INFLUENCED

Lymphocyte subset analysis in QuantiFERON-TB Gold Plus and T-Spot.TB for latent tuberculosis infection in rheumatoid arthritis.

  • Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy
  • 2018
VIEW 1 EXCERPT

References

Publications referenced by this paper.
SHOWING 1-10 OF 20 REFERENCES

SPICE: exploration and analysis of post-cytometric complex multivariate datasets.

  • Cytometry. Part A : the journal of the International Society for Analytical Cytology
  • 2011
VIEW 1 EXCERPT