Combined Action of Histone Reader Modules Regulates NuA4 Local Acetyltransferase Function but Not Its Recruitment on the Genome.

@article{Steunou2016CombinedAO,
  title={Combined Action of Histone Reader Modules Regulates NuA4 Local Acetyltransferase Function but Not Its Recruitment on the Genome.},
  author={Anne-Lise Steunou and Myriam Cramet and Dorine Rossetto and Maria J. Aristizabal and Nicolas Lacoste and Simon Drouin and Val{\'e}rie C{\^o}t{\'e} and Eric R. Paquet and Rhea T. Utley and Nevan J. Krogan and François Robert and Michael S. Kobor and Jacques C{\^o}t{\'e}},
  journal={Molecular and cellular biology},
  year={2016},
  volume={36 22},
  pages={2768-2781}
}
Recognition of histone marks by reader modules is thought to be at the heart of epigenetic mechanisms. These protein domains are considered to function by targeting regulators to chromosomal loci carrying specific histone modifications. This is important for proper gene regulation as well as propagation of epigenetic information. The NuA4 acetyltransferase… CONTINUE READING