Combined ART started during acute HIV infection protects central memory CD4+ T cells and can induce remission.

Abstract

BACKGROUND Therapeutic control of HIV replication reduces the size of the viral reservoir, particularly among central memory CD4+ T cells, and this effect might be accentuated by early treatment. METHODS We examined the effect of ART initiated at the time of the primary HIV infection (early ART), lasting 2 and 6 years in 11 and 10 patients, respectively… (More)
DOI: 10.1093/jac/dkv084

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Cite this paper

@article{Chret2015CombinedAS, title={Combined ART started during acute HIV infection protects central memory CD4+ T cells and can induce remission.}, author={Antoine Ch{\'e}ret and Charline Bacchus-Souffan and V{\'e}ronique Av{\'e}ttand-F{\'e}no{\"{e}l and Adeline M{\'e}lard and Georges Nembot and Catherine Blanc and Assia Samri and Asier S{\'a}ez-Ciri{\'o}n and Laurent Hocqueloux and Caroline Lascoux-Combe and Clotilde Allavena and C{\'e}cile Goujard and Marc Antoine Valantin and Anne Leplatois and Laurence Meyer and Christine Rouzioux and Brigitte Autran}, journal={The Journal of antimicrobial chemotherapy}, year={2015}, volume={70 7}, pages={2108-20} }