Combinatorial transcriptional regulation: the interaction of transcription factors and cell signaling molecules with homeodomain proteins in Drosophila development.

@article{Bondos2001CombinatorialTR,
  title={Combinatorial transcriptional regulation: the interaction of transcription factors and cell signaling molecules with homeodomain proteins in Drosophila development.},
  author={Sarah E. Bondos and Xianhui Tan},
  journal={Critical reviews in eukaryotic gene expression},
  year={2001},
  volume={11 1-3},
  pages={145-71}
}
Patterning and cell fate specification during development require complex interplay among multiple families of transcription factors to establish, maintain, and coordinate transcriptional cascades. During these processes, homeodomain proteins and cell signaling proteins cooperate to generate tissue-and stage-specific responses. This review of physical and genetic interactions in Drosophila melanogaster development highlights the cross-talk among these protein families. Protein-protein… CONTINUE READING

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