Combinatorial regulation of transcription factors and microRNAs

  title={Combinatorial regulation of transcription factors and microRNAs},
  author={Naifang Su and Yufu Wang and Minping Qian and Minghua Deng},
  booktitle={BMC Systems Biology},
Gene regulation is a key factor in gaining a full understanding of molecular biology. Cis-regulatory modules (CRMs), consisting of multiple transcription factor binding sites, have been confirmed as the main regulators in gene expression. In recent years, a novel regulator known as microRNA (miRNA) has been found to play an important role in gene regulation. Meanwhile, transcription factor and microRNA co-regulation has been widely identified. Thus, the relationships between CRMs and microRNAs… CONTINUE READING
Highly Cited
This paper has 25 citations. REVIEW CITATIONS


Publications citing this paper.
Showing 1-10 of 14 extracted citations


Publications referenced by this paper.
Showing 1-10 of 29 references

p53-repressed miRNAs are involved with E2F in a feed-forward loop promoting proliferation

Molecular systems biology • 2008
View 14 Excerpts
Highly Influenced