Combinatorial negative regulation of glucose-responsive genes in yeast

Abstract

53 tion for parallel analysis of sets of target sequences. The method employs arrayed primers that bind specific padlock probes and initiate rolling-circle replication. A localized, linear concatemer is generated that is detected by fluorescence microscopy in a microarray format. Recently we have shown that padlock probes can also be ligated on RNA template… (More)
DOI: 10.1038/14333

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