Combinatorial cell-3D biomaterials cytocompatibility screening for tissue engineering using bioinspired superhydrophobic substrates.

@article{Salgado2012CombinatorialCB,
  title={Combinatorial cell-3D biomaterials cytocompatibility screening for tissue engineering using bioinspired superhydrophobic substrates.},
  author={Christiane Laranjo Salgado and Mariana M. B. Oliveira and Jo{\~a}o F Mano},
  journal={Integrative biology : quantitative biosciences from nano to macro},
  year={2012},
  volume={4 3},
  pages={318-27}
}
We report on the development of a new array-based screening flat platform with the potential to be used as a high-throughput device based on biomimetic polymeric substrates for combinatorial cell/3D biomaterials screening assays in the context of tissue engineering. Polystyrene was used to produce superhydrophobic surfaces based on the so-called lotus effect. Arrays of hydrophilic regions could be patterned in such surfaces using UV/ozone radiation, generating devices onto which combinatorial… CONTINUE READING
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