Combinatorial approaches to the prevention and treatment of HIV-1 infection.

Abstract

The discovery of the human immunodeficiency virus type 1 (HIV-1) in 1982 soon led to the identification and development of antiviral compounds to be used in treatment strategies for infected patients. Early in the epidemic, drug monotherapies frequently led to treatment failures because the virus quickly developed resistance to the single drug. Following… (More)
DOI: 10.1128/AAC.00976-10

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Cite this paper

@article{Pirrone2011CombinatorialAT, title={Combinatorial approaches to the prevention and treatment of HIV-1 infection.}, author={Vanessa Pirrone and Nina J Thakkar and Jeffrey M. Jacobson and Brian Wigdahl and Fred C Krebs}, journal={Antimicrobial agents and chemotherapy}, year={2011}, volume={55 5}, pages={1831-42} }