Combinatorial antigenotoxic and anticarcinogenic effects of tomato and garlic through modulation of xenobiotic-metabolizing enzymes during hamster buccal pouch carcinogenesis.
@article{Bhuvaneswari2005CombinatorialAA, title={Combinatorial antigenotoxic and anticarcinogenic effects of tomato and garlic through modulation of xenobiotic-metabolizing enzymes during hamster buccal pouch carcinogenesis.}, author={V. Bhuvaneswari and S. Abraham and S. Nagini}, journal={Nutrition}, year={2005}, volume={21 6}, pages={ 726-31 } }
OBJECTIVE
Combination chemoprevention by dietary agents is a promising approach toward cancer control. Many dietary agents are known to prevent experimental mutagenesis and carcinogenesis by modulating xenobiotic-metabolizing enzymes. The present study evaluated the combinatorial chemopreventive effects of tomato and garlic on hamster buccal pouch carcinogenesis induced by 7,12-dimethylbenz[a]anthracene (DMBA).
METHODS
Hamsters were assigned to one of four groups. The right buccal pouches of… CONTINUE READING
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References
SHOWING 1-10 OF 39 REFERENCES
Combination chemoprevention by tomato and garlic in the hamster buccal pouch carcinogenesis model
- Biology
- 2004
- 19
Chemopreventive efficacy of lycopene on 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis.
- Biology, Medicine
- Fitoterapia
- 2001
- 93
Dose-response effect of tomato paste on 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis.
- Chemistry, Medicine
- Journal of experimental & clinical cancer research : CR
- 2004
- 12
Effects of garlic on 7,12-Dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis.
- Chemistry, Medicine
- Cancer detection and prevention
- 1999
- 61
S-Allylcysteine, a Garlic Constituent, Inhibits 7,12-Dimethylbenz[a]Anthracene-Induced Hamster Buccal Pouch Carcinogenesis
- Biology, Medicine
- Nutrition and cancer
- 2001
- 25
Modulatory influence of garlic and tomato on cyclooxygenase-2 activity, cell proliferation and apoptosis during azoxymethane induced colon carcinogenesis in rat.
- Biology, Medicine
- Cancer letters
- 2004
- 72
Sequential Changes in the Cellular Redox State During 7,12-Dimethylbenz[a]anthracene-Induced Carcinogenesis in the Hamster Buccal Pouch
- Chemistry, Medicine
- Toxicology mechanisms and methods
- 2003
- 5
Chemoprevention of aflatoxin B1-induced carcinogenesis by indole-3-carbinol in rat liver--predicting the outcome using early biomarkers.
- Biology, Medicine
- Carcinogenesis
- 1998
- 87
- PDF
Radioprotection of mice following garlic pretreatment.
- Chemistry, Medicine
- The British journal of cancer. Supplement
- 1996
- 35
Chemoprotection against cancer by phase 2 enzyme induction.
- Chemistry, Medicine
- Toxicology letters
- 1995
- 446