Combinatorial Therapies After Spinal Cord Injury: How Can Biomaterials Help?

  title={Combinatorial Therapies After Spinal Cord Injury: How Can Biomaterials Help?},
  author={Tobias Fuehrmann and Priya N. Anandakumaran and Molly S Shoichet},
  journal={Advanced healthcare materials},
  volume={6 10}
Traumatic spinal cord injury (SCI) results in an immediate loss of motor and sensory function below the injury site and is associated with a poor prognosis. The inhibitory environment that develops in response to the injury is mainly due to local expression of inhibitory factors, scarring and the formation of cystic cavitations, all of which limit the regenerative capacity of endogenous or transplanted cells. Strategies that demonstrate promising results induce a change in the microenvironment… CONTINUE READING
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