Combinational adenovirus-mediated gene therapy and dendritic cell vaccine in combating well-established tumors

Abstract

Recent developments in tumor immunology and biotechnology have made cancer gene therapy and immunotherapy feasible. The current efforts for cancer gene therapy mainly focus on using immunogenes, chemogenes and tumor suppressor genes. Central to all these therapies is the development of efficient vectors for gene therapy. By far, adenovirus (AdV)-mediated… (More)
DOI: 10.1038/sj.cr.7310032

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