Combination therapy with aspirin, clopidogrel and warfarin following coronary stenting is associated with a significant risk of bleeding.

@article{Khurram2006CombinationTW,
  title={Combination therapy with aspirin, clopidogrel and warfarin following coronary stenting is associated with a significant risk of bleeding.},
  author={Zakaria Khurram and Eric T. Chou and Robert M. Minutello and Geoffrey Bergman and Manish Parikh and Srihari S Naidu and Shing Chiu Wong and Mun Kyung Hong},
  journal={The Journal of invasive cardiology},
  year={2006},
  volume={18 4},
  pages={162-4}
}
Dual antiplatelet therapy of aspirin and a thienopyridine is the standard of care following coronary stenting. Patients who are on chronic warfarin therapy and receive a coronary stent need to be treated with the triple therapy of aspirin, clopidogrel and warfarin; however, the bleeding risk in these patients is unknown. To evaluate the bleeding risk in patients requiring chronic warfarin therapy and undergoing stent implantation, we compared 107 consecutive patients on chronic warfarin therapy… CONTINUE READING

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