Combination therapy versus monotherapy as initial treatment for stage 2 hypertension: a prespecified subgroup analysis of a community-based, randomized, open-label trial.

@article{Everett2008CombinationTV,
  title={Combination therapy versus monotherapy as initial treatment for stage 2 hypertension: a prespecified subgroup analysis of a community-based, randomized, open-label trial.},
  author={Brendan M. Everett and Robert J Glynn and Eleanor Danielson and Paul M. Ridker},
  journal={Clinical therapeutics},
  year={2008},
  volume={30 4},
  pages={661-72}
}
BACKGROUND Current guidelines suggest consideration of initial combination therapy for patients with stage 2 hypertension, but rates of hypertension treatment and control in clinical practice vary according to age, race, sex, and body mass index (BMI). OBJECTIVE This was a prespecified subgroup analysis of one of the primary efficacy end points-mean change in systolic blood pressure (SBP) at 6 weeks -in a previously published community-based, randomized, open-label trial comparing valsartan… CONTINUE READING

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