Combination therapy in recent onset rheumatoid arthritis: a randomized double blind trial of the addition of low dose cyclosporine to patients treated with low dose chloroquine.

@article{Borne1998CombinationTI,
  title={Combination therapy in recent onset rheumatoid arthritis: a randomized double blind trial of the addition of low dose cyclosporine to patients treated with low dose chloroquine.},
  author={Ben E. E. M. van den Borne and Robert B.M. Landew{\'e} and H S Goei Th{\'e} and J. H. Rietveld and Aeilko H. Zwinderman and George A. W. Bruyn and Ferdinand C. Breedveld and Ben A. C. Dijkmans},
  journal={The Journal of rheumatology},
  year={1998},
  volume={25 8},
  pages={1493-8}
}
OBJECTIVE To investigate whether there is interaction between chloroquine and cyclosporine (CyA) at the level of efficacy and toxicity in patients with recent onset rheumatoid arthritis (RA). METHODS Eighty-eight patients with recent onset RA, who had shown a suboptimal clinical response on low dose chloroquine monotherapy, were randomly assigned to… CONTINUE READING