Combination therapy in multiple sclerosis

@article{Milo2011CombinationTI,
  title={Combination therapy in multiple sclerosis},
  author={R. Milo and H. Panitch},
  journal={Journal of Neuroimmunology},
  year={2011},
  volume={231},
  pages={23-31}
}
  • R. Milo, H. Panitch
  • Published 2011
  • Medicine
  • Journal of Neuroimmunology
  • The multifaceted pathogenesis of multiple sclerosis (MS) involves complex interactions between the immune and the central nervous systems which provide a multitude of targets for therapeutic interventions. Current therapies for MS are only partially effective. One potential strategy to increase treatment efficacy is the combination of two or more drugs with complementary mechanisms of action, which may result in additive or synergistic therapeutic effects. In this review, we discuss the… CONTINUE READING
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    References

    SHOWING 1-10 OF 87 REFERENCES
    Review: Innovative monoclonal antibody therapies in multiple sclerosis
    • 16
    The mechanism of action of methylprednisolone in the treatment of multiple sclerosis
    • 136
    Oral simvastatin treatment in relapsing-remitting multiple sclerosis
    • 464
    • PDF
    Emerging multiple sclerosis oral therapies
    • 38
    Diverse Targets for Intervention during Inflammatory and Neurodegenerative Phases of Multiple Sclerosis
    • 159
    • PDF
    Concepts of induction and escalation therapy in multiple sclerosis
    • P. Rieckmann
    • Medicine
    • Journal of the Neurological Sciences
    • 2009
    • 46