Combination radiofrequency thermal ablation and adjuvant IV liposomal doxorubicin increases tissue coagulation and intratumoural drug accumulation.

@article{Ahmed2004CombinationRT,
  title={Combination radiofrequency thermal ablation and adjuvant IV liposomal doxorubicin increases tissue coagulation and intratumoural drug accumulation.},
  author={M. Ahmed and Shraga Nahum Goldberg},
  journal={International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group},
  year={2004},
  volume={20 7},
  pages={781-802}
}
There has been marked interest in minimally-invasive, image-guided radiofrequency (RF) tumour ablation (i.e. coagulating tumour using short duration heating ( < 15 min) by directly applying temperatures > 50 degrees C via needle electrodes) to treat focal liver, renal, breast, bone and lung tumours. In spite of advances in RF technology and improved understanding of tumour biophysiology that now enable experimental treatment of tumours up to 5cm, investigators have been unable to achieve… CONTINUE READING

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