Combination of rifapentine-moxifloxacin-minocycline (PMM) for the treatment of leprosy.

  title={Combination of rifapentine-moxifloxacin-minocycline (PMM) for the treatment of leprosy.},
  author={Baohong Ji and J Grosset},
  journal={Leprosy review},
  volume={71 Suppl},
To further the development of a multidrug regimen for treatment of leprosy that is suitable for monthly administration and fully supervisable, the bactericidal activities against Mycobacterium leprae of HMR 3647 (HMR), moxifloxacin (MXFX) and rifapentine (RPT) were measured by the proportional bactericide technique in the mouse footpad system, and compared with those of the established antileprosy drugs clarithromycin (CLARI), ofloxacin (OFLO) and rifampicin (RMP). Administered in five daily… CONTINUE READING

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