Combination of reverse transcriptase PCR analysis and immunoglobulin M detection on filter paper blood samples allows diagnostic and epidemiological studies of measles.

@article{Swart2001CombinationOR,
  title={Combination of reverse transcriptase PCR analysis and immunoglobulin M detection on filter paper blood samples allows diagnostic and epidemiological studies of measles.},
  author={Rik L de Swart and Yusuf Nur and Ahmed Abdallah and H. Kruining and Haja Sittana El Mubarak and Salah Ahmed Ibrahim and Bernadette van den Hoogen and Jan Groen and Albert D M E Osterhaus},
  journal={Journal of clinical microbiology},
  year={2001},
  volume={39 1},
  pages={270-3}
}
As measles control and elimination campaigns progress, laboratory confirmation of clinically diagnosed measles cases becomes increasingly important. However, in many tropical countries collection and storage of clinical specimens for this purpose are logistically complicated. In this study it is shown that blood samples spotted on filter paper are suitable for the laboratory diagnosis of measles using a combination of reverse transcriptase PCR (RT-PCR) analysis and immunoglobulin M (IgM… CONTINUE READING
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Measles

  • T. F. Wild
  • VACCINES
  • 1999

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