Combination of microsurgery and gene therapy for spinal dorsal root injury repair.

@article{Liu2009CombinationOM,
  title={Combination of microsurgery and gene therapy for spinal dorsal root injury repair.},
  author={Song Liu and Delphine Bohl and Stephane R Blanchard and Josette Bacci and G{\'e}rard Sa{\"i}d and J F Heard},
  journal={Molecular therapy : the journal of the American Society of Gene Therapy},
  year={2009},
  volume={17 6},
  pages={992-1002}
}
Brachial plexus injury is frequent after traffic accident in adults or shoulder dystocia in newborns. Whereas surgery can restore arm movements, therapeutic options are missing for sensory defects. Dorsal root (DR) ganglion neurons convey sensory information to the central nervous system (CNS) through a peripheral and a central axon. Central axons severed through DR section or avulsion during brachial plexus injury inefficiently regenerate and do not reenter the spinal cord. We show that a… CONTINUE READING