Combination of melphalan and dexamethasone for patients with newly diagnosed POEMS syndrome.

Abstract

POEMS syndrome is a rare clonal plasma cell disorder without standard treatment. Based on the efficacy and low toxicity of a combination of melphalan and dexamethasone (MDex) for light chain amyloidosis, we conducted a prospective study of MDex treatment for patients with newly diagnosed POEMS syndrome. Thirty-one patients (19 men) were enrolled and the… (More)
DOI: 10.1182/blood-2010-12-328112

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