Combination of intravenous S-ketamine and oral tranylcypromine in treatment-resistant depression: A report of two cases

@article{Bartova2015CombinationOI,
  title={Combination of intravenous S-ketamine and oral tranylcypromine in treatment-resistant depression: A report of two cases},
  author={L. Bartova and S. Vogl and M. Stamenkovic and N. Praschak-Rieder and M. Willeit},
  journal={European Neuropsychopharmacology},
  year={2015},
  volume={25},
  pages={2183-2184}
}
  • L. Bartova, S. Vogl, +2 authors M. Willeit
  • Published 2015
  • Psychology, Medicine
  • European Neuropsychopharmacology
  • Ketamine, a rapid-acting antidepressant and anti-suicidal agent, is thought to increase brain monoamine levels by enhancing monoamine release or inhibiting presynaptic monoamine-reuptake. Here we present two female inpatients suffering from treatment-resistant depression with recurrent severe suicidal crises receiving a combination of intravenous S-ketamine and oral tranylcypromine, which is a well-known irreversible monoamine oxidase (MAO) inhibitor. Since inhibition of monoamine-reuptake with… CONTINUE READING
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