Combination of gadolinium and dysprosium chelates as a cellular integrity marker in MR imaging.

@article{Ericsson1995CombinationOG,
  title={Combination of gadolinium and dysprosium chelates as a cellular integrity marker in MR imaging.},
  author={Anders Ericsson and Tore Bach-Gansmo and Frank Niklasson and Anders Hemmingsson},
  journal={Acta radiologica},
  year={1995},
  volume={36 1},
  pages={41-6}
}
A combination of gadolinium (Gd) and dysprosium (Dy) chelates was investigated as a potential marker of cell-membrane integrity by means of a double-contrast effect in MR imaging. Blood samples with varying hematocrit (Hct) levels containing intact or lysed cells were used as model systems. With intact cells, the agents were assumed to be distributed solely extracellularly and the highest Hct studied (69%) was assumed to mimic the ratio of extracellular to intracellular water in tissue. The… CONTINUE READING

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