Combination of external-beam radiotherapy with intraoperative electron-beam therapy is effective in incompletely resected pediatric malignancies.

@article{Oertel2006CombinationOE,
  title={Combination of external-beam radiotherapy with intraoperative electron-beam therapy is effective in incompletely resected pediatric malignancies.},
  author={Susanne Oertel and Andreas G. Niethammer and Robert Krempien and Falk Roeder and Michael J. Eble and Claudia Baer and Peter E Huber and Andreas Kulozik and K. -L. Waag and Martina Treiber and J{\"u}rgen Debus},
  journal={International journal of radiation oncology, biology, physics},
  year={2006},
  volume={64 1},
  pages={
          235-41
        }
}
PURPOSE Intraoperative electron-beam radiotherapy (IOERT) has been applied for local dose escalation in over 1,400 patients in Heidelberg since 1991. Among these were 30 children, in 18 of whom IOERT was employed in radiation treatment with external-beam radiotherapy (EBRT) on account of incomplete resection. We address the question whether IOERT is able to compensate for microscopic or macroscopic tumor residue if employed in the overall radiation regimen. METHODS AND MATERIALS The data of… CONTINUE READING